RECENT RESEARCH

Evidence of microglial activation in autism and its possible role in brain underconnectivity (2012)
Juan I. Rodriguez and Janet K. Kern Evidence of microglial activation in autism and its possible role in brain underconnectivity. Neuron Glia Biology, Available on CJO doi:10.1017/S1740925X12000142

Does microglial dysfunction play a role in autism and Rett syndrome? (2012)
Does microglial dysfunction play a role in autism and Rett syndrome?. Neuron Glia Biology, Available on CJO 2012 doi:10.1017/S1740925X1200004X

Microglial Activation in Young Adults With Autism Spectrum Disorder (2013)
Microglial Activation in Young Adults With Autism Spectrum Disorder. JAMA Psychiatry. 2013;70(1):49-58. doi:10.1001/jamapsychiatry.2013.272

Microglia in development: linking brain wiring to brain environment (2012)
Rosa C. Paolicelli and Cornelius T. Gross Microglia in development: linking brain wiring to brain environment. Neuron Glia Biology, Available on CJO doi:10.1017/S1740925X12000105

Nobel winner ties mental illness to immune defect - microglial activation (2010)?
Published: Thursday, May 27, 2010 - Link to Video

Microglia in the Cerebral Cortex in Autism (2012)
Tetreault NA, Hakeem AY, Jiang S, Williams BA, Allman E, Wold BJ, Allman JM. J Autism Dev Disord. 2012 Mar 31.

Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism (2012)
Morgan JT, Chana G, Abramson I, Semendeferi K, Courchesne E, Everall IP. Brain Res. 2012 May 25;1456:72-81.

The role of enteric glia in gut inflammation (2010)
Georg von Boyen and Martin Steinkamp (2010). The role of enteric glia in gut inflammation. Neuron Glia Biology, 6 , pp 231-236 doi:10.1017/S1740925X11000068

Sex, glia, and development: Interactions in health and disease (2012)
Jaclyn M. Schwarz and Staci D. Bilbo (2012). Horm Behav. 2012 Feb 22. [Epub ahead of print] Duke University, Department of Psychology and Neuroscience, 572 Research Dr. Rm 3017, Durham, NC 27705, USA

Microglia and neuronal cell death (2012)
José L. Marín-Teva, Miguel A. Cuadros, David Martín-Oliva and Julio Navascués Microglia and neuronal cell death. Neuron Glia Biology, Available on CJO 2012 doi:10.1017/S1740925X12000014

The role of microglia at synapses in the healthy CNS: novel insights from recent imaging studies (2012)
Marie-Ève Tremblay The role of microglia at synapses in the healthy CNS: novel insights from recent imaging studies. Neuron Glia Biology, Available on CJO 2012 doi:10.1017/S1740925X12000038

Nitric oxide signaling in brain function, dysfunction, and dementia (2010) - Pubmed Link
Steinert JR, Chernova T and Forsythe ID (2010). Neuroscientist. 2010 Aug;16(4):435-52. Neurotoxicity at the Synaptic Interface, MRC Toxicology Unit, University of Leicester, Leicester, UK.

NIH-supported study shows how immune cells change wiring of the developing mouse brain (2012)
Schafer, D. et al. "Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner" Neuron, May 24, 2012.


NIH Supported Study: Immune cell (Microglia) in the brain swallows synapses to sculpt neurons during development

A microglial cell (green) from the developing mouse brain is shown in 3-D. Synapses from neurons projecting from the eyes (labeled red or blue) are engulfed and seen inside the microglial cell. From Schafer et al., Neuron, May 24, 2012.

AUTISM DISEASE PROCESS

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Autism Disease Process

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PUBLICATION

May 2010 Study published by a Nobel Prize Winning geneticist ties mental illness to immune system dysfunction...

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November 2004 Study published by Johns Hopkins Medicine provides evidence that the brain's immune system is triggered in autism...

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